Abstract: Assume $(M, \omega)$ is a connected, compact 6 dimensional symplectic manifold equipped with a semi-free Hamiltonian circle action, such that the fixed point set consists of isolated points or compact orientable surfaces. We restrict attention to the case $\dim$$H^2(M)<3$. We give a complete list of the possible manifolds, determine their equivariant cohomology ring and equivariant Chern classes. Some of these manifolds are classified up to diffeomorphism. We also show the existence of these manifolds. Assume $(M, \omega)$ is a connected, compact 6 dimensional symplectic manifold equipped with a semi-free Hamiltonian circle action, such that the fixed point set consists of isolated points or compact orientable surfaces. We restrict attention to the case $\dim$$H^2(M)<3$. We give a complete list of the possible manifolds, determine their equivariant cohomology ring and equivariant Chern classes. Some of these manifolds are classified up to diffeomorphism. We also show the existence of these manifolds.